Last Updated on January 4, 2024 by The Health Master
Within the next seven years, researchers anticipate developing vaccines that can help prevent catastrophic illnesses like cancer and heart diseases, SkyNews reported.
According to reports, the pharmaceutical company Moderna, which created one of the most effective COVID-19 vaccines, is working on “personalized” vaccines that will specifically target various tumor types.
Dr Paul Burton, the chief medical officer of Moderna, predicted that the therapy will be “highly effective” and might save “many hundreds of thousands if not millions of lives” by the year 2030.
Ground-breaking research could result in a single injection that protects against COVID-19, the flu, and the respiratory syncytial virus (RSV).
mRNA therapies, which teach cells how to make a protein that activates the body’s immune response, may be used to treat disorders for which there are presently no effective treatments, stated SkyNews.
Research on cancer has shown ‘tremendous promise’ says Dr Burton
According to Dr Burton, research on cancer, as well as infectious, cardiovascular, autoimmune, and uncommon disorders, has shown “tremendous promise”.
Burton while speaking to The Guardian said that he believes, “We will have mRNA-based therapies for rare diseases that were previously undruggable, and I think 10 years from now, we will be approaching a world where you can truly identify the genetic cause of the disease and, with relative simplicity, go and edit that out and repair it using mRNA-based technology.”
How will personalized vaccines function?
Before using genetic sequencing to find mutations, doctors take a biopsy of the patient’s tumor to start the process of immunising against cancer.
The immune system may be triggered by certain mutations that are responsible for the formation of the malignancy, according to an algorithm.
An mRNA molecule is created with instructions for creating antigens that trigger an immunological response. Once injected, the mRNA is translated into proteins that are the same as those on cancer cells.
Then, immune cells that are carrying the same proteins as cancer cells crash with them and kill them, SkyNews reported.
Burton added: “I think what we have learned in recent months is that if you ever thought that mRNA was just for infectious diseases, or just for COVID, the evidence now is that that’s absolutely not the case.
It can be applied to all sorts of disease areas; we are in cancer, infectious disease, cardiovascular disease, autoimmune diseases, rare disease. We have studies in all of those areas and they have all shown tremendous promise.”
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