Vitamin D overuse can lead to this serious issue: PGI Doctor

The study lends ample support to the fact that vitamin D can be used as an effective adjuvant treatment modality in patients hospitalised with C-19

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Last Updated on July 8, 2021 by The Health Master

“Use of vitamin D in high doses, especially injectable preparations, to prevent C-19 should be strongly discouraged. Vitamin D supplemented prior to the diagnosis of C-19 was not found to improve clinical outcomes in our meta-analysis. Instead, overuse can lead to vitamin D toxicity,” said Prof Sanjay K Bhadada from the Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh.

Promising results

“As the C-19 pandemic continues, search for an effective therapy still remains elusive. Accordingly, multiple existing drugs have been repurposed for the management of C-19. In this context, vitamin D, a fat-soluble vitamin which is primarily related to bone and mineral metabolism, has shown some promising results in C-19,” read the study.
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Doctors at the PGI, Chandigarh, have recently published a study in the Journal of Endocrinological Investigation entitled “Vitamin D supplementation and clinical outcomes in C-19: a systematic review and meta-analysis”.

The study was conducted by Dr Rimesh Pal, Dr Mainak Banerjee, Prof Sanjay K Bhadada, Dr Anirudh J Shetty, Dr Birgurman Singh and Dr Abhinav Vyas. “Pooled data from 13 studies showed that vitamin D supplemented

after the diagnosis of C-19 leads to improved clinical outcomes in terms of reduced mortality and/or intensive care unit admission,” said Prof Sanjay K Bhadada, Head of Endocrinology Department at the PGI, Chandigarh.

“As the C-19 pandemic continues to rampage, search for an effective therapy still remains elusive. Accordingly, multiple existing drugs have been repurposed for the management of C-19. In this context, vitamin D, a fat-soluble vitamin which is primarily related to bone and mineral metabolism, has shown some promising results in C-19,” read the study.

“The study lends ample support to the fact that vitamin D can be used as an effective adjuvant treatment modality in patients hospitalised with C-19. The anti-viral and the immune-modulatory role of vitamin D are perhaps helpful in this regard. Nevertheless, irrational and rampant use of vitamin D to prevent C-19 should not a norm,” it further reads.

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