Single vaccine shot 96.6% effective: ICMR

The analysis looked at the outcome of all vaccines administered in India till 15 August, about 54.58 crore doses


Last Updated on September 11, 2021 by The Health Master

New Delhi: A single dose of any Covid vaccine is 96.6 per cent effective in preventing mortality, while with two doses the effectiveness goes up to 97.5 per cent, analysis by the Indian Council of Medical Research (ICMR) has found.

The analysis looked at the outcome of all vaccines administered in India till 15 August, about 54.58 crore doses.

The ICMR analysis is important because it is based on real-world data and also because India has among the longest gaps between two doses of the Covishield vaccine — 12 to 16 weeks.

In most countries, the dose gap is in the four to six weeks range, though there have been some recent studies that found that immunogenicity is boosted if the gap is as high as 11 months (44 weeks).

Injection vaccine Medicine
Picture: Pixabay

India has been administering Covishield, Covaxin, and some amounts of Sputnik V, though Covishield forms the bulk of the vaccine doses administered.

The ICMR is also in the process of putting together a Covid-19 vaccine tracker, by integrating data from the CoWin portal, its own testing database, and the health ministry’s website.

“The data shows that the effectiveness of the first dose in preventing mortality is 96.6 per cent and for the second dose it is 97.5 per cent. It works across all age groups, that is why we are appealing to everybody to get vaccinated.



We are also looking at reinfections and breakthrough infections, but we are not worried about breakthrough infections per se because these are disease-modifying vaccines.

Contracting the disease either after first dose or after both doses may happen, but the outcome will not go to serious disease,”  ICMR Director General Dr Balram Bhargava said, during the Centre’s Covid briefing.

Dr Bhargava also advocated low key celebrations in view of the upcoming festive season. “Responsible travel rather than revenge travel should be practised and masks should be used at all times,” he said.

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