Scientists recommend alternative to Remdesivir

With the shortage of Remdesivir, the combination can be used to save the lives of severe C-19 patients.

Picture: Pixabay

NEW DELHI:  At a time when the country is facing a shortage of Remdesivir, scientists have investigated 61 antiviral drugs and found a combination that has superior anti-SARS-CoV-2 potential.

A team of scientists from the Biochemical Sciences Division, CSIR-National Chemical Laboratory, India Academy of Scientific and Innovative Research (AcSIR), Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, and INTOX Private Limited, Pune, worked on the efficacy of drug repurposing for treating C-19.

Medicine Injection
Picture: Pixabay

To read more articles on Remdesivir, click here

“Our analysis suggested Sofosbuvir in combination with Ledipasvir and Daclatasvir as potential therapeutic agents for C-19. The combined score suggests that these combinations have superior anti-SARS-CoV-2 potential than Remdesivir and other investigational drugs,” they said in a paper published in Current Science.

They said the present work provides a rationale-based approach to select drugs with possible anti-C-19 activity for further clinical evaluation.

With the shortage of Remdesivir, the combination can be used to save the lives of severe C-19 patients. 

“Drug repurposing has been utilised as the most preferred therapeutic intervention for C-19 mitigation due to its necessity and feasibility. To prioritise therapeutic regime against C-19, we used 61 antiviral drugs and their combinations,” said the paper.

The team said the findings provide a scientific rationale for applying Ledipasvir and Daclatasvir in combination with Sofosbuvir for C-19 management.

Also read:

Govt to include psoriasis drug acitretin in Schedule H

India, US collaboration in Pharma Sector

Zydus Cadila’s Virafin priced at Rs 11,995 per dose

PCI asks Pharmacy institutions to prepare timetable for online classes

Bharat Biotech begins direct supply of COVAXIN to 14 states

Vivimed Labs gets DGHS nod to Mfr Favipiravir tablets in India

Subscribe for daily free updates on Telegram

Follow us on Facebook and Linkedin

For daily free updates on WhatsApp, click here

Enter your email address:

Delivered by FeedBurner