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Drug doses as per IP

Drug doses as per Indian Pharmacopoeia (IP).

Rakesh Dahiya

December 10, 2022

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Rakesh Dahiya

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Food and Drugs Administration, (FDA) Haryana, India. |
Email ID: dahiya19@yahoo.com

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Last Updated on October 2, 2024 by The Health Master

Drug Doses As Per IP

The Govt. of India has created a separate, dedicated, autonomous institution in the form of the Indian Pharmacopoeia Commission (IPC) to deal with matters relating to the timely publication of the Indian Pharmacopoeia (IP)

Indian Pharmacopoeia (IP) is the official book of standards for drugs included therein, in terms of the Second Schedule to the Drugs and Cosmetics Act, of 1940.

Drug doses are given in the Indian Pharmacopoeia (IP). Let’s have a look:

Click for more on IPC and IP

NAME OF DRUG	INITIAL DOSE	MAINTENANCE / REGULAR DOSE	Parenteral Dose
Acebutolol HCl		“Antihypertensive: Initially, 400 mg once daily; increased after 2 weeks to 400 mg twice daily. Antianginal: Initially, 400 mg once daily or 200 mg twice daily; in severe angina, 300 mg thrice daily; maintenance dose, up to 1.2 gm daily. Asantiarrhythmic, 400 mg to 1.2 gm daily, in 2 to 3 divided doses.”
Acetazolamide	500mg	250mg/every 6 Hrs
Activated Charcoal		50 gm
Adrenaline			200-500mcg sc or im
Albendazole		Nematodal infestation 400mg,
Allopurinol	100mg Single Dose gradually increased to 300mg daily	200 to 400 mg Daily in divided dosage
Alpha-Amylase		200 to 500mg
Alprazolam		250 to 500 mcg TDS
Amantadine HCl		100 mg daily, increased to 200mg daily in 2 divided dosage
Amikacin			Up to 1.5gm daily in 2 divided dosages by IM, slow IV or inf.

Amiloride HCl	5 to 10 mg daily	Maximum 20 mg daily
Aminocaproic Acid	5 gm Orally and by slow inf,	1 to 1.25 gm every Hr. Not more than 30 gm per 24 Hr,
Aminophylline		100 to 300 mg	250 to 500 mg
Amitriptyline HCl	50 to 75 mg daily in divided doses	50 to 100 mg daily in divided doses
Ammonium Chloride		3 to 6 gm daily in divided doses
Amodiaquine	400 mg Weekly	400 to 600 mg daily for 3 days
Amoxycillin Sodium			1 to 3gm daily in divided doses IM or IV
Amoxycillin Trihydrate		750mg to 4.5gm daily in divided doses
Amphotericin B		Up to 200mg every 6 hrs.	250mcg/Kg body weight daily. increased to 1mg daily or 1.5 mg per Kg on alternate days
Ampicillin		2 to 6 gm daily in divided doses

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Ampicillin Sodium			1 to 3 gm of Ampicillin daily in divided doses IM or IV
Ampicillin Trihydrate		2 to 6 gm daily in divided doses
Analgin		500mg to 3gm daily in divided doses
Ascorbic Acid		Prophylactic: 25 to 75 mg daily; Therapeutic, not less than 250 mg daily, in divided doses
Aspirin		As analgesic / antipyretic, 300 to 600 mg four to six times a day; as antirheumatic, 1 to 2 gm four to six times a day, up to 10 gm dailyasantithrombotic, 75mg daily
Astemizole		“Adults, 10 mg once daily up to 7 days. Children, 5 mg once daily up to 7 days.”
Atenolol		50 to 100 mg, daily, in 1 or 2 doses
Atropine Methonitrate		For treatment of congenital hypertrophic pyloric stenosis in infants, 200 to 600 mcg half an hour before feeds.
Atropine Sulphate	400 to 600 mcg four to six times a day sc, IM, or IV; as an antidote to cholinesterase inhibitors by IV inj. 2 to 4 mg initially, followed by IM inj. 2 mg repeated every 5 to 10 minutes.	Anticholinergic, orally.250mcg to 2mg daily in single or divided doses	400 to 600 mcg four to six times a day sc, IM, or IV; as an antidote to cholinesterase inhibitors by IV inj. 2 to 4 mg initially, followed by IM inj. 2 mg repeated every 5 to 10 minutes.
BCG Vaccine(Freeze Dried)			Prophylactic, ic inj. As a single dose, 0.1 ml

Beclomethasone Dipropionate		By inhalation, Adult, 2 inhalations, each of 50 mcg, three or four times a day up to max. of 20 inhalations in 24 hrs Child, 1 or 2 inhalations, each of 50 mcg, three or four times a day up to a max. Of 10 inhalations in 24 hrs.
Belladonna Dry Extract		15 to 60 mg.
Benzathine Penicillin		Orally, 3 lake Units to 6 lake Units every 6 hrs.	3 lake Units to 10 lake Units IM Prophylactic, by IM inj. 12 lake Units every 2 or 3 weeks.
Benzhexol HCl.	1 mg	Gradually increased to a usual maintenance dose of 5 to 15 mg daily in 3 to 4 divided doses.
Benzylpenicillin Potassium			The equivalent of 1.2 to 2.4 gm of benzylpenicillin daily, in 4 divided doses by IM or by slow iv or by infusion.
Benzylpenicillin Sodium			The equivalent of 1.2 to 2.4 gm of benzylpenicillin daily, in 4 divided doses by IM or by slow iv or by infusion.
Betamethasone		0.5 to 05 mg daily in divided doses.
Betamethasone Sod. Phosphate			The equivalent of 0.5 to 5 mg of Betamethasone daily, in divided doses. Acute adrenal insufficiency, by iv or IM inj., is the equivalent of 10 to 80 mg of Betamethasone daily in divided doses.
Bisacodyl		5 to 10 mg daily.
Bismuth Subcarbonate		1 to 4 gm.

Bleomycin Sulphate			By inj. The equivalent of 15 to 30 Units of Bleomycin weekly in divided doses.
Bromhexine HCl.		8 to 16 mg three to four times daily.
Bromocriptine Mesylate		The equivalent of 2.5 to 20 mg of Bromocriptine daily in divided doses.
Bupivacaine HCl			By infiltration anaesthesia, the equivalent of 2 mg of anhydrous Bupivacaine Hcl per Kg body weight.
Buprenorphine HCl		Sublingually, up to 400 mcg every 6 to 8 hrs.	300 to 600 mcg every 6 to 8 hrs; IM or slow IV;
Busulphan	2 to 4 mg daily	Maintenance dose, 0.5 to 2 mg daily.
Caffeine		300 to 600 mg
Calcium Carbonate		1 to 5 gm.
Calcium Chloride		1 to 2 gm	5 to 10 ml of 10 % w/v solution by slow iv
Calcium Folinate			Up to 120 mg in divided doses over 12 to 24 hrs by IM or IV inj. Or infusion followed by 12 to 15 mg IM or 15 mg orally every 6 hrs for the next 48 hrs.

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Calcium Gluconate		Up to 15 gm daily, in divided doses	1 to 2 gm by IM or slow iv Inj.
Calcium Lactate		Up to 8 gm daily, in divided doses.
Calcium Levulinate			1 gm once a day, by IM or iv. Inj.
Calcium Pantothenate		10 to 100 mg daily, in divided doses
Captopril	12.5 to 50 mg twice daily	The usual maintenance dose, is 25 mg twice daily, maximum, 50 mg twice daily.
Carbamazepine	200 mg daily	Increasing to 1.2 gm daily, in divided doses, in accordance with the needs of the patient.
Carbenicillin Sodium			By iv inj., the equivalent of 12 to 30 gm of Carbenicillin daily, in divided doses; by IM inj., the equivalent of 4 to 8 gm of Carbenicillin daily, in divided doses.
Carbenoxolone Sodium		300 mg daily, in divided doses for 1 week; subsequently, up to 150 mg daily, in divided doses.
Carbidopa		10 to 25 mg in combination with Levodopa
Carbimazole	Controlling dose, 30 to 60 mg daily, in divided doses	Maintenance dose, 5 to 20 mg daily.

Castor Oil	5 to 15 ml.
Cefadroxil	500 mg to 2 gm daily, in divided doses.
Cefazolin Sodium		1 to 4 gm daily in divided doses, by IM or IV or infusion.
Cefotaxime Sodium		“1 to 2 gm of Cefotaxime Every 8 to 12 hrs by IM or IV Inj.; By infusion, 1 to 2 gm given over 20 to 60 minutes. For children, the equivalent of 100 to 150 mg of Cefotaxime per kg body weight daily in 2 to 4 divided doses increasing to 200 mg per kg of body weight daily, if necessary.”
Ceftazidime		1 to 2 gm, every 8 to 12 hrs, by IM or slow IV or IV infusion.
Cefuroxime Sodium	250 mg twice daily	750 to 1.5 gm, every 6 to 8 hrs, by IM or IV or IV infusion.
Cephalexin	1 to 4 gm daily, in divided doses.
Cephlorididine		1 to 4 gm daily, in divided doses, by iv, IM or deep sc inj.
Chlorambucil	100 to 200 mcg per kg of body weight daily for 4 to 8 weeks.
Chloramphenicol	Adult, 1.5 to 3 gm daily, in divided doses; for a child, 25 to 50 mg per kg of body weight daily, in divided doses.

Chloramphenicol Palmitate	Adult, the equivalent of 1.5 to 3 gm of Chloramphenicol daily, in divided doses; for a child, the equivalent of 25 to 50 mg of Chloramphenicol per kg of body weight daily, in divided doses.
Chloramphenicol Sodium Succinate		The equivalent of 3 to 4 gm of Chloramphenicol daily, in divided doses, by IV inj.
Cholecalciferol	“Rickets; not more than 800 units daily. For the treatment of rickets &osteomalacia, 5000 to 50000 Units daily For the treatment of hypocalcaemia and hypoparathyroidism, 50000 to 200000 Units daily.”	200000 to 400000 Units by IM inj.
Chlordiazepoxide	10 to 100 mg daily, in divided doses.
Chloroquine Phosphate	“Prophylactic,300 mg once weekly; therapeutic, initial dose, 600 mg followed by a single dose of 300 mg after 6 to 8 hrs and then by a single dose of 300 mg daily for the next 2 to 4 days & in hepatic amoebiasis 600 mg daily for 5 to 7 days followed by 300 mg to 450 mg daily or twice a week for 2 weeks or longer	By IM inj. 160 to 200 mg repeated intervals of 12 hrs until oral therapy is possible as Antimalarial and in hepatic amoebiasis
Chloroquine Sulphate	Prophylactic, 300 mg once weekly; therapeutic, initial dose, 600 mg followed by a single dose of 300 mg after 6 to 8 hrs and then by a single dose of 300 mg daily for the next 2 to 4 days & in hepatic amoebiasis 600 mg daily for 5 to 7 days followed by 300 mg to 450 mg daily or twice a week for 2 weeks or longer	“By IM inj. 160 to 200 mg repeated intervals of 12 hrs until oral therapy is possible as Antimalarial and in hepatic amoebiasis
Chlorpheniramine Maleate	4 to 16 mg daily, in divided doses	10 to 20 mg, by sc or IM inj. Repeated if required; maximum 40 mg in 24 hrs. By slow iv inj. over 1 minute, 10 to 20 mg diluted in the syringe with 5 to 10 ml of blood.
Chlorpromazine HCl	As antipsychotic, 75 to 300 mg daily, in divided doses; As antiemetic, 10 to 25 mg every 4 to 6 hrs.	As an antipsychotic, by IM inj. 25 to 50 mg. As antiemetic, by deep im inj. 25 mg initially followed by 25 to 50 mg every 3 to 4 hrs until necessary.
Chlorpropamide	100 to 500 mg daily.
Chlorthalidone	50 to 200 mg daily.

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Cholera Vaccine			“For adults and children over 10 years, by sc inj., initial dose, 0.5 ml; second dose, 1.0 ml after an interval of 4 to 6 weeks. For children 2 to 10 years, the initial dose 0.3 ml; second dose 0.3 ml. For children 1 to 2 years, initial dose, 0.2 ml; second dose 0.2ml.”
Chorionic Gonadotrophin			By IM inj, 500 to 5000 units twice weekly or in accordance with the needs and response of the patient.
Ciprofloxacin			100 to 200 mg twice daily by infusion.
Ciprofloxacin HCl		The equivalent of 250 to 750 mg of Ciprofloxacin twice daily.
Cisplastin			By iv infusion, 15 to 20 mg per sq. m. of body surface daily for 5 days.
Clofazimine	For leprosy, for previously untreated patients, 100 mg 3 times weekly;	For sulphone-resistant patients, 100 mg 6 times weekly. For the suppression of lepra reactions, 200 mg daily.
Clonidine HCl		50 to 100mcg thrice daily increased gradually according to the needs & response of the patient; maximum daily dose 1.2 mg.	By slow IV inj., 150 to 300 mcg; maximum daily dose 750 mcg.
Cloxacillin Sodium		The equivalent of 500 mg of Cloxacillin every 6 hrs, at least 30 minutes before food;	By IM inj. 250 mg every 4 to 6 hrs; by slow IV inj. or by infusion, 500 mg every 4 to 6 hrs.
Codeine Phosphate		30 to 60 mg every 4 hrs when necessary, to a maximum of 200 mg daily.
Colchicine	1 mg	Subsequent doses, 500 mcg every two hrs.

Colchicine & Probenecid Tabs	Colchicine 1 mg & Probenecid, 250 mg twice daily after food.
Concentrated Glyceryl Trinitrate Solution”	Sublingually (as Tablet), 300 mcg to 1 mg, repeated as required.
Cortisone Acetate	25 to 37.5 mg daily, in divided doses	By IM inj. 50 to 400 mg daily, in single or divided doses.
Cyanocobalamin		For treatment of megaloblastic anaemia, by IM inj. 1 to 2 mg in divided doses, in the first week. Subsequent doses, 250 mcg weekly until the blood count is normal, maintenance dose, 250 mcg every 3 or 4 weeks.
Cyclophosphamide	100 to 150 mg daily	By IV inj. 100 to 150 mg daily.
Cyclserine	500 mg to 1 gm daily, in divided doses.
Cyproheptadine HCl	4 to 20 mg daily, in divided doses.
Cytarabine		To be determined by the physician.
Danazol	200 to 800 mg daily, in divided doses.
Dapsone	100 mg daily.

Dehydroemetine HCl		By deep IM inj. 60 to 90 mg daily.
Desferrioxamine Mesylate	After gastric lavage, 5 to 10 gm in 50 to 100 ml of liquid;	By IM inj. 1 to 2 gm in 10 to 20 ml of Water for Inj. every 3 to 12 hrs; by continuous iv infusion, upto 15 mg per kg per hour with a maximum of 80 mg per kg in 24 hrs.
Dexamethasone	500 mcg to 10 mg daily, in divided doses.
Dexamethasone Sodium Phosphate		In the treatment of adrenal insufficiency, by IM or slow IV or infusion, 0.5 to 10 mg. In shock, by IV inj, or infusion, 2 to 6 mg per kg body weight, repeated if necessary after 2 to 6 hrs. In cerebral oedema, by IV inj., 10 mg initially, then 4 mg by IM inj. every 6 hrs as required for 2 to 10 days.
Dextromethorphan HCl	10 to 30 mg every 4 to 8 hrs.
Diazepam	In anxiety states, 2 mg thrice daily, increased if necessary to 15 to 30 mg daily, in divided doses; in insomnia associated with anxiety, 5 to 15 mg at bedtime	By IM or slow IV inj. 10 mg repeated if necessary after 4 hrs.
Diclofenac Sodium	25 to 75 mg.	25 to 75 mg.
Dicyclomine HCl	30 to 60 mg daily, in divided doses. An oral Solution is required to be diluted; the diluted solution should be freshly prepared.
Dienoestrol	In the treatment of menopausal symptoms, 500 mcg to 5 mg daily; in the treatment of prostate carcinoma and mammary carcinoma, 15 to 30 mg daily; for suppression of lactation, 15 mg thrice daily for 3 days, followed by 15 mg daily fir 6 days.
Diethylcarbamazine Citrate	150 to 500 mg daily.

Digoxin	“For rapid digitalisation,1to 1.5 mg in divided doses over 24 hrs; for less urgent digitalisation,250 to 500mcg daily; For paediatric use, 10 to 35 mcg per kg body weight in 3 or 4 divided doses over 24 hrs followed by 4 to 10 mcg per kg body weight daily”	“Maintenance dose, 62.5 to 500 mcg daily. For paediatric maintenance dose, 250 mcg once or twice daily.”	By IV infusion inj. 750 mcg to 1 mg.
Diloxanide Furoate		1.5 gm daily, in divided doses.
Diltiazem HCl	30 to 60 mg thrice daily;	Maximum 480 mg daily
Diluted Isosorbide Dinitrate		“Sublingually, 5 to 10 mg in angina; Orally, 30 to 120 mg daily, in divided doses.”
Diluted pentaerythritol Tetranitrate		The equivalent of 20 to 60 mg of pentaerythritol tetranitrate, 3 to 4 times daily.
Dimercaprol			By IM inj., 2 to 3mg per kg of body weight every 4 hrs during the first day and subsequently, in accordance with the needs of the patient.
Dimethicone		40 to 100 mg, four times daily.
Diphenhydramine HCl		50 to 200 mg daily, in divided doses.
Diphenoxylate HCl		5 to 30 mg daily, in divided doses.
Disodium Edetate			By IV inj. 50 mg per kg of body weight, up to a maximum of 3 gm per day.

Disulfiram	500 mg as a single dose for 1 to 2 weeks	Maintenance dose, 125 to 500 mg daily.
Dothiepin HCl	Initially 75 mg daily, in divided doses,	Increased gradually, as necessary, to 150 mg daily.
Doxepin HCl	Initially, the equivalent of 75 mg of Doxipen daily,in divided doses	Increased gradually to a maximum of 300 mg daily, in divided doses.
Doxorubicin HCl			To be determined by the physician in accordance with the needs of the patient.
Doxycycline HCl	The equivalent of 200 mg of Doxycycline on the first day	Followed by 100 mg daily.
D-Panthenol		250 to 500 mg.
Dydrogesterone		10 mg twice daily.
Emetine HCl			By sc or IM inj. 30 to 60 mg daily.
Enalapril Maleate	Initial, 2.5 to 5 mg daily	Maintenance dose, 10 to 20 mg daily; maximum 40 mg daily.
Ephedrine		15 to 60 mg.

Ergocalciferol		“Rickets; not more than 800 units daily. For the treatment of rickets & osteomalacia, 5000 to 50000 Units daily For the treatment of hypocalcaemia and hypoparathyroidism, 50000 to 200000 Units daily.”	200000 to 400000 Units by IM inj.
Ergometrine Maleate		250 mcg to 1 mg;	By IM inj. 200 to 500 mcg; by IV inj. 100 to 500 mcg.
Ergotamine Tartrate		1 to 2 mg ;	By sc or IM inj. 250 to 500 mcg.
Erythromycin		1 to 2 gm daily, in divided doses.
Erythromycin Estolate		1 to 2 gm daily, in divided doses.
Erythromycin Stearate		1 to 2 gm daily, in divided doses.
Ethambutol HCl	15 to 25 mg per kg of body weight daily, for 2 months,	Followed by 15 mg per kg body weight daily.
Ethinyloestradiol		“For menopausal symptoms, 10 to 20 mcg daily continuously or for 21 days, repeated after 7 days, with a progestogen from day 17 to day 26 of the cycle if the uterus is intact. For primary amenorrhoea, 10 mcg on alternate days increasing to a maximum of 50 mcg daily continuously with a progestogen for the last 5 days of the month.”
Ethionamide		250 to 375 mg daily, usually in a three-drug regimen with Rifampicin And Dapsone
Ethionamide		250 to 375 mg daily, usually in a three-drug regimen with Rifampicin And Dapsone

Ethosuximide	“500 mg daily, in divided doses; For child, 50 to 125 mg twice daily;”	“Increasing to 2 gm as necessary For child, increasing to 250 mg, three to four times daily, as necessary.”
Ethyloestrenol		2 to 4 mg daily.
Fenfluramine HCl	Initially, 20 mg morning & evening	Increasing to a maximum of 80 mg twice daily, preferably half an hour before breakfast.
Ferrous Fumarate		Prophylactic, 200 mg daily; therapeutic, 400 to 600 mg daily, in divided doses.
Ferrous Gluconate		Prophylactic, 600 mg daily; therapeutic, 1.2 to 1.8 gm daily, in divided doses.
Ferrous Sulphate		Prophylactic, 300 mg; therapeutic 600 to 900 mg daily in divided doses.
Fludrocortisone Acetate		In adrenocortical insufficiency, 50 to 300 mcg daily.
Fluphenazine Decanoate			By deep IM inj. test dose 6.25 to 12.5 mg, thereafter 4 to 7 days 12.5 to 100 mg repeated as required.
Fluphenazine HCl		1 to 2 mg twice daily, in anxiety states; 2.5 to 10 mg daily in 2 to 3 divided doses in schizophrenia & other psychoses	By IM inj. 1.25 to 10 mg daily.
Flurbiprophen		150 to 200 mg, daily in divided doses, increased in acute conditions to 300 mg daily.

Folic Acid	“In the treatment of megaloblastic anaemia associated with folic acid deficiency, 5 to 20 mg daily. In the prophylaxis of megaloblastic anaemia of, 200 to 500 mcg daily.”
Fortified Benzathine Penicillin Inj.		To be determined by the Physician in accordance with the needs of the patient.
Frusemide	In oedema, 20 to 40 mg daily; in oliguvria, 250 mg 4 to 6 times daily;	By IM or slow IV inj. 20 to 50 mg
Furazolidone	400 mg daily, in divided doses.
Fusidic Acid	500 mg to 1 gm every 8 hrs.
Gentamicin Sulphate		By IM or slow IV inj. over at least 3 minutes or by iv infusion, 2 to 5 mg per kg body weight daily, in divided doses.
Glibenclamide	5 mg daily, adjusted according to response; maximum 15 mg daily, after food.
Griseofulvin	500 mg to 1 gm daily, in divided doses.
Guaiphenesin	“Adult: 200 to 400 mg every four hrs; Child aged: 6 to 12 yrs, 100 to 200 mg every four hrs; Child: 2 to 6 yrs, 50 to 100 mg every four hrs.”
Gugulipid	500 mg, equivalent to 25 mg of gugulsterones, thrice daily.

Haloperidol	1.5 to 20 mg daily, in divided doses;	By IM or IV inj. 2 to 10 mg.
Heavy Magnesium Carbonate	“As antacid; 300 to 600 mg; As laxative, 2 to 4 gm.”
Heavy Magnesium Oxide	“As antacid; 300 to 600 mg; As laxative, 2 to 4 gm.”
Heparin Sodium		Prophylactic, by sc inj. 10000 to 15000 Units daily, in divided doses; therapeutic, by IV inj. 20000 to 50000 Units daily, in divided doses.
Hyaluronidase		By sc or IM, inj. 1500 Units either mixed with the inj. fluid or injected into the site before inj. is administered.
Hydralazine HCl	25 to 50 mg twice daily;	By slow IV inj. 5 to 20 mg over 20 minutes; may be repeated after about 30 minutes.
Hydrochlorothiazide	25 to 100 mg.
Hydrocortisone	Adrenocortical insufficiency, 20 to 30 mg daily, in divided doses;	By IM inj. or by slow IV inj. or infusion, 100 to 500 mg, 3 to 4 times in 24 hrs or as required.
Hydrocortisone Acetate		By intra- articular inj. or local infiltration, 5 to 50 mg.
Hydrocortisone Hemisuccinate		By IV inj., the equivalent of 100 to 500 mg of Hydrocortisone 3 to 4 times in 24 hrs or as required.

Hydroxocobalamin		In the treatment of megaloblastic anaemia, by IM inj. 1 to 2 mg in divided doses, in the first week; subsequent doses, 250 mcg weekly until the blood count is normal; maintenance dose, 1 mg every two months.
Hydroxyprogesterone Hexanoate		By IM inj. 250 to 500 mg weekly during the first half of.
Hyoscine Butylbromide	20 mg four times daily;	By IM or IV inj. 20 mg, repeated after 30 minutes if necessary.
Hyoscine HBr	In the prevention of motion sickness, 300 mcg 30 minutes before commencing journey and repeated every 6 hrs;	If required; by sc or IM inj. for pre-anaesthetic medication, 200 to 600 mcg.
Ibuprofen	600 mg to 1.2 gm daily, in divided doses, after food.
Imipramine HCl.	50 to 150 mg daily, in divided doses.
Indomethacin	50 to 200 mg daily, in divided doses, with food
Isoniazid	300 mg daily or up to 1 gm twice weekly.
Isoprenaline HCl.		By iv infusion, 0.5 to 2 mcg per minute, usually administered after dilution with Dextrose Inj.
Isoprenaline Sulphate	5 to 20 mg daily.

Isoxuprine HCl.		As vasodilator, 20 mg 4 times daily;	“As vasodilator ,by im inj. 5 to 10 mg upto 4 times daily; By infusion, initially, 100 mcg per minute, increased to 500 mcg per minute if required As uterine relaxant, by IV infusion, initially, 200 mcg to 300 mcg per minute gradually increased to 500 mcg per minute until labour is arrested; subsequently by IM inj 10 mg every 3 hrs for 24 hrs, then every 4 to 6 hrs for 48 hrs; then orally, 20 mg 4 times daily.”
Ispaghula Husk		3 to 5 gm.
Kanamycin			“By IM inj. the equivalent of 500 mg to 1 gm of Kanamycin daily, in divided doses By slow iv infusion, 15 to 30 mg per kg body weight daily, in divided doses, every 8 to 12 hrs.”
Ketamine HCl.			By slow IV inj. the equivalent of 1 to 2 mg of Ketamine per kg of body weight over 60 seconds, repeated according to the patient’s response; by deep IM inj. the equivalent of 4 to 10 mg of Ketamine per kg body weight, repeated according to patients’ response.
Ketoconazole		“Adult: 200 mg to 400 mg once daily with food for 14 days Child: 3 mg per kg body weight daily.”
Ketoprofen		100 to 200 mg daily, in 2 to 4 divided doses, with food.
Labetalol HCl.	Initially, 100 mg twice daily with food;	Increased at fortnightly intervals to usual dose of 200 mg twice daily; up to 88 mg daily in divided doses; maximum 2.4 gm daily;	By IV inj. 50 mg over 1 minute, repeated after 5 minutes, if necessary; maximum 200mg.
Levamisole HCl		The equivalent of 150 mg of Levamisole as a single dose.
Levodopa	Initially, 125 to 500 mg daily, in divided doses after meals,	Increasing gradually in accordance with the needs of the patient; optimal dose, 1 to 8 gm daily. Usually used in combination with Carbidopa.
Levonorgestrel		As a contraceptive, 150 to 250 mcg in combination with 20 to 50 mcg of ethinyloestradiol daily.

Light Kaolin	15 to 75 gm.
Light Magnesium Carbonate	“As antacid; 300 to 600 mg; As laxative, 2 to 4 gm.”
Light Magnesium Oxide	“As antacid; 300 to 600 mg; As laxative, 2 to 4 gm.”
Lignocaine HCl	Local anaesthetic, up to 200 mg as a single dose, when given with adrenaline; as antiarrhythmic, by iv infusion, 50 mg to 100 mg at the rate of 1 to 2 mg per minute.
Lincomycin HCl	The equivalent of 500 mg of Lincomycin every 6 to 8 hrs, 30 minutes before food;	By IM inj. the equivalent of 600 mg of Lincomycin every 12 to 24 hrs; by slow iv infusion, the equivalent of 600 mg of Lincomycin every 8 to 12 hrs.
Liquid Paraffin	10 to 30 ml.
Liquid Paraffin Emulsion	10 to 30 ml.
Lithium Carbonate	250 to 2 gm daily, in divided doses.
Lomustine	120 to 130 mg per sq. m. body surface every 6 to 8 weeks.
Magaldrate	800 mg to 1.6 gm.

Magnesium Hydroxide	“As antacid, 500 to 750 mg; As laxative, 2 to 4 gm.”
Magnesium Sulphate	2 to 16 gm.
Magnesium Trisilicate	500 mg to 2 gm repeated in accordance with the needs of the patient.
Malt Extract	4 to 16 ml.
Mannitol		“As a diuretic, by iv infusion, 50 to 200 gm over 24 hrs but not more than 50 gm on one occasion preceded by a test dose of 200 mg per kg of body weight by slow IV inj. As diagnostic aid, by IV inj. 200 mg per kg body weight in a 15 to 25 % w/v solution.”
Mebendazole	For threadworm infestation, 100 mg as a single dose; for other infestations, 100 mg twice daily, for three days.
Mebeverine HCl	135 mg thrice daily, preferably 20 minutes before meals.
Meclizine HCl	25 to 50 mg daily.
Mefenamic Acid	250 to 500 mg thrice daily, after food.
Megestrol Acetate	40 to 320 mg daily, in divided doses.

Melphalan	2 to 4 mg daily, for 4 to 6 days;	By inj. 50 mg.
Menadione	2 to 10 mg daily	2 to 10 mg daily
Mentha Oil	60 to 200 mcl.
Mercaptopurine	100 to 200 mg daily, in divided doses.
Metformin HCl	0.5 to 3 gm daily, in divided doses.
Methdilazine HCl	8 mg two to 4 times daily.
Methotrexate	“Adults: 2.5 to 10 mg; Child: 2.5 to 5 mg.”	“Adults: 2.5 to 10 mg; Child: 2.5 to 5 mg.”
Methoxamine HCl		“By IM inj. 10 to 15 mg; By slow IV inj. 5 to 10 mg.”
Methyldopa	The equivalent of 0.5 to 3 gm of anhydrous Methyldopa daily, in divided doses.
Methylergometrine Maleate	250 mcg to 500 mcg;	By sc, IM or IV inj. 100 mcg to 200 mcg.

Methylprednisolone		4 to 48 mg daily, in divided doses.
Methylprednisolone Acetate			By deep IM inj. 40 to 120 mg.
Metoclopramide HCl		The equivalent of 10 to 30 mg of anhydrous Metoclopramide HCl daily, in divided doses;	By IM or IV inj. the equivalent of 10 mg of anhydrous Metoclopramide HCl.
Metoprolol Tartrate	The initial dose should not exceed 100 mg daily.	100 to 450 mg daily, in divided doses.
Metronidazole		“Trichomoniasis; 200 mg thrice daily, for 7 days Giardiasis: Adults, 2 gm daily for 3 days Child, 1 gm daily & for infants 400mg daily. Amoebiasis: 400 mg thrice daily, for 5 to 10 days”	Initial dose, by iv infusion 15 mg per kg of body weight; subsequent doses, 7.5 mg per kg of body weight up to a maximum of 1 gm every six hrs, for 7 days or longer.
Metronidazole Benzoate		Amoebiasis: the equivalent of 400 mg of Metronidazole thrice daily, for 5 to 10 days
Morphine Sulphate		10 to 20 mg	By sc or IM inj. 10 to 20 mg.
Nalidixic Acid		2 to 4 gm daily, in divided doses.
Nandrolone Decanoate			By IM inj. 25 to 50 mg, every 3 weeks.
Nandrolone Phenylpropionate			By IM inj. 25 to 50 mg, every 3 weeks.

Neostigmine Bromide		15 to 30 mg repeated at suitable intervals; the total daily dose, is 75 to 300 mg.
Neostigmine Methylsulphate			By sc or IM inj. 1 to 2.5 mg, repeated at suitable intervals; the total daily dose, is 5 to 20 mg.
Niclosamide		2 gm as a single dose after a light breakfast followed by a purgative 2 hrs later.
Nicotinamide		“Prophylactic: 15 to 30 mg daily; Therapeutic: 50 to 250 mg daily;”	By IV inj. 50 to 250 mg daily.
Nicotinic Acid		“Prophylactic: 15 to 30 mg daily; Therapeutic: 50 to 250 mg daily;”
Nifedipine	Up to, 30 mg daily, in divided doses	As per the needs of the patient.
Nitrazepam		5 to 10 mg daily, at bedtime.
Nitrofurantoin		50 to 150 mg four times daily.
Noradrenaline Bitartrate			By iv infusion, 2 to 20 mcg per minute, as per the blood pressure of the patient.
Norethisterone		5 to 20 mg daily, in single or divided doses.

Norfloxacin		600 mg to 1.6 gm daily, in divided doses.
Norgestrel		As contraceptive: 150 to 300 mcg in combination with 20 to 50 mcg of ethinyloestradiol daily.
Nortriptyline HCl	Initially, 20 to 40 mg daily;	Maintenance dose, 30 to 75 mg daily.
Noscapine		15 to 30 mg three to four times daily.
Nystatin		For alimentary candidiasis, 1000000 to 2000000 Units daily, in divided doses.
Oestradiol Benzoate			By IM inj. 1 to 2 mg daily.
Omeprazole	For Zollinger-Ellison syndrome, initially 60 mg once daily; the usual range is 20 to 120 mg daily.	“For duodenal & gastric ulcers and for reflux oesophagitis, 20 to 40 mg daily;
“Ormeloxifene HCl ( Centchroman HCl )		30 mg twice a week, 3 days apart, for three months and thereafter once a week.
Oxyphenbutazone		200 to 400 mg daily, in divided doses.
Oxyprenolol HCl	“As antihypertensive, initially 80 mg twice daily, As antiarrhythmic, initially, 20 to 40 mg thrice daily, increased as necessary.	“As antihypertensive, increased as required at weekly intervals; maximum 480 mg daily. As antianginal, 40 to 160 mg thrice daily.”

Oxytetracycline		250 to 500 mg every 6 hrs;	By IM inj. 1 to 2 gm daily.
Oxytetracycline HCl		250 to 500 mg every 6 hrs;	By IV infusion. In a con. Of 0.1 % w/v, 1 to 2 gm daily.
Oxytocin			“Induction or enhancement of labour; iv drip infusion of a 5 % Dextrose Solution containing 1 IU Oxytocin per 100 ml.3rd stage labour & puerperium; 5 to 10 IU, IM or 5 IU, iv slowly. Caesarian section; 5 IU intramurally after delivery.”
Pancreatin		500 mg to 1 gm.
Papain		120 to 600 mg.
Paracetamol		500 to 1 gm every 4 to 6 hrs, up to 4 gm daily, in divided doses.
Paraldehyde			By deep IM inj. as a single dose, 5 to 10 ml; by rectal inj. 5 to 10 ml, suitably diluted with physiological saline.
Penicillamine	In rheumatoid arthritis, the initial dose, is 125 to 250 mg daily before food, increased gradually every 4 to 12 weeks until remission occurs; the usual maintenance dose, is 500 to 750 mg daily.	In poisoning, 500 mg to 2 gm daily, in divided doses or in accordance with the needs of the patient.
Penicillin G Benzathine
Pentazocine			By sc, IM or iv inj. 30 to 60 mg every 3 to 4 hrs.

Pentazocine HCl		25 to 100 mg, every 3 to 4 hrs after food.
Pentazocine Lactate			By sc, IM or iv inj. 30 to 60 mg every 3 to 4 hrs.
Pepsin		300 mg to 1 gm.
Pethidine HCl		50 to 150 mg every 4 hrs;	By sc or IM inj. 25 to 100 mg every 4 hrs; by slow IV inj. 25 to 50 mg every 4 hrs.
Phenformin HCl		50 to 100 mg daily, in divided doses.
Phenindamine Tartrate		75 to 150 mg daily, in divided doses.
Phenindione	Initially, 200 to 300 mg;	Subsequently 25 to 100 mg daily, as per the needs of the patient.
Pheniramine Maleate		25 to 50 mg daily, in divided doses.	By IM or slow IV inj 22.5 to 45 mg daily, in divided doses.
Phenobarbitone		60 to 300 mg at night.
Phenobarbitone Sodium		60 to 300 mg at night.	By IM or IV inj. 50 to 200 mg, repeated after 6 hrs if necessary; maximum 600 mg daily.

Phenolphthalein		30 to 200 mg.
Phenoxymethylpenicillin Potassium		“Adult: the equivalent of 250 to 500 mg of Phenoxymethylpenicillin every 6 hrs, at least 30 minutes before food. Child: every 6 hrs up to one year, 62.5 mg; 1 to 5 yrs, 125 mg; and 6 to 12 yrs, 250 mg.”
Phentolamine Mesylate			By IV inj. 5 to 10 mg.
Phenylbutazone		100 to 600 mg daily, in divided doses, with or after food.
Phenylephrine HCl			By sc or IM inj. 2 to 5 mg; by slow IV inj 100 to 500 mcg; by iv infusion 5 to 20 mg in 500 ml, adjusted according to the response.
Phenytoin Sodium	Anticonvulsant: 150 to 300 mg daily, increasing gradually to 600 mg as per the needs of the patient;	“Status epileptics: by slow IV inj. 10 to 15 mg per kg at a rate not exceeding 50 mg per minute as a loading dose; maintenance doses of 100 mg thereafter every 6 hrs. Arrhythmias: by IV inj. 3.5 to 5 mg per kg at a rate not exceeding 50 mg per minute and repeated once if necessary.”
Pholcodine		Up to 40 mg daily, in divided doses.
Phthalylsulphathiazole		2 to 12 gm daily, in divided doses.
Physostigmine Salicylate			By sc or IM inj. 600 mcg to 1.2 mg.
“Piperazine Adipate, Piperazine Citrate, Piperazine Hydrate, Piperazine Phosphate”		“Adult: The equivalent of 1 to 2gm of Piperazine Hydrate daily, in divided doses. For 7 days; Roundworm: the equivalent of 4.5 gm of Piperazine Hydrate as a single dose. Child: For threadworm; the equivalent of 40 mg of Piperazine Hydrate per kg of body weight daily, in divided doses for 7 days. Roundworm: as a single dose, the equivalent of 120 mg of Piperazine Hydrate per kg of body weight, up to a maximum dose of 4 gm.”

Piroxicam	10 to 20 mg daily.
Potassium Chloride	“Prophylactic: 2 to 4 gm daily; Therapeutic: 10 to 15 gm daily.”
Potassium Citrate	4 to 10 gm.
Potassium Iodide	In the preoperative treatment of thyrotoxicosis, 30 to 60 mg; as an expectorant, 250 to 500 mg.
Pralidoxime Chloride		By IV inj. 1 to 2 gm as a 5 % w/v solution, administered over a period of not less than 5 minutes; by IM inj. 1 gm initially, followed by 1 to 2 gm further doses if necessary, up to a maximum of 12 gm in 24 hrs.
Prazosin HCl	500 mcg to 1 mg two to three times daily.
Prednisolone	Up to 30 mg daily, in divided doses.
Prednisone	5 to 60 mg daily, in divided doses
Primaquine Phosphate	The equivalent of 15 mg of Primaquine, once a day for 14 days.
Probenecid	250 to 500 mg twice daily.

Procainamide HCl	500 mg to 1.5 gm daily, in divided doses;	By slow IV inj. 500 mg to 1.5 gm daily, in divided doses;
Procaine Penicillin		By IM inj. 300 to 900 mg daily.
Prochlorperazine Maleate	“Antipsychotic; 15 to 100 mg daily, in divided doses, Antiemetic: 10 to 30 mg daily, in divided doses.
Prochlorperazine Mesylate		“Antipsychotic; By IM inj. 12.5 to 25 mg, twice or thrice daily, Antiemetic: By im inj.12.5 mg.
Proguanil HCl “Promethazine HCl,	Suppressive, 100 to 300 mg daily.
Promethazine Theoclate”	20 to 50 mg daily, in single or divided doses.	20 to 50 mg daily, in single or divided doses.
Propantheline Br.	15 mg 3 times daily one before meals and 30 mg at night; maximum 120 mg daily.
Propranolol HCl	20 mg to 2 gm daily, in divided doses; the initial dose should not exceed 40 mg;	By slow IV inj. 3 to 10 mg.
Propylthiouracil	300 to 450 mg daily, in divided doses.
Propyphenazone	105 to 3 gm daily, in divided doses.

Protamine Sulphate		By slow IV inj. over a 10-minute period. 1 mg for every 100 Units of heparin remaining in the patient if given within 15 minutes; maximum 50 mg.
Pseudoephedrine HCl	60 mg three to four times daily.
Pyrazinamide	Up to 35 mg per kg of body weight daily, in divided doses.
Pyrimethamine	Used in combination with Sulphadoxine (25 mg ) or Dapsone ( 12.5 mg )
Quinalbarbitone Sodium	100 to 200 mg.
Quinidine Sulphate	“Cardiac Arrhythmia: 200 mg daily in Three or 4 divided doses. Arterial fibrillation: 200 to 400 mg every 2 to 4 hrs, up to 3 gm daily.”
“Quinine Bisulphate, Quinine Sulphate”	“Suppressive, 300 to 600 mg daily; Therapeutic: 1.2 to 2 gm daily, in divided doses.”
Quinine Dihydrochloride	“Suppressive, 300 to 600 mg daily; Therapeutic: 1.2 to 2 gm daily, in divided doses.”	By slow IV inj. 300 to 600 mg.
Quiniodochlor	750 mg to 1.5 gm daily, in divided doses.
Ranitidine HCl	The equivalent of 300 to 600 mg of Ranitidine, in divided doses.	By IM or slow IV inj. the equivalent of 50 mg of Ranitidine, every 6 to 8 hrs.

Reserpine	500 mcg daily.
Rifampicin	“Adult: 450 to 600 mg daily preferably before breakfast. Child: up to 20 mg per kg daily to a maximum of 600 mg.”
“Salbutamol, Salbutamol Sulphate”	6 to 16 mg daily, in divided doses.	By sc or IM inj. 500 mcg repeated every 4 hrs, if necessary; By slow IV inj, 250 mcg, repeated if necessary.
Salbutamol Sulphate	The equivalent of 6 to 16 mg daily, in divided doses.	By sc or IM inj. 500 mcg repeated every 4 hrs, if necessary; By slow IV inj, the equivalent of 250 mcg, of Salbutamol or by infusion, the equivalent of 3 to 20 mcg of Salbutamol per minute.
Sodium Bicarbonate	1 to 4 gm
Sodium Citrate	1 to 10 gm
SodiumDihydrogen Phosphate Dihydrate	2 to 4 gm.
Sodium Fusidate	1.5 gm daily, in divided doses.
Sodium Lactate Inj.		By iv infusion at the rate of 5 ml or less per minute.
Sodium Valproate	600 mg to 1.6 gm daily, in divided doses.

Spironolactone		100 to 200 mg daily, in divided doses.
Stilboestrol		“Menopausal symptoms: 100 mcg to 1 mg daily; Suppression of Lactation: 5 mg thrice daily for 3 days followed by 5 mg daily for 6 days; Carcinoma of the prostate and mammary carcinoma, 10 to 20 mg daily.”
Streptokinase			By iv infusion, 250000 to 6000000 Units over 30 minutes followed by 100000 Units every hr for up to one week.
Streptomycin Sulphate			By IM inj. the equivalent of 500 mg to 1 gm of Streptomycin daily, or at longer intervals.
Succinylcholine Chloride			By IV inj. 20 to 100 mg, as per the needs of the patient.
Succinylsulphathiazole		10 to 20 gm daily in divided doses.
Sulphadiazine	3 gm;	Subsequent dose, up to 4 gm daily, in divided doses.
Sulfadimethoxine	1 to 2 gm,	Subsequent doses are 500 mg daily.
Sulphadimidine	“Systemic Infections: 3 gm UTI: 2 gm”	“Systemic Infections: subsequent doses, up to 6 gm daily, in divided doses UTI: subsequent doses, up to 4 gm daily in divided doses.”
Sulphadimidine Sodium			By IM or IV inj. 1 to 5 gm.

Sulphadoxine	Initially, 2 gm	Subsequent doses, 1 to 1.5 gm weekly.	By deep IV inj. 2.5 gm initially, followed by 1.5 gm after four days.
Sulphafurazole	“Systemic Infections: 3 gm UTI: 2 gm”	“Systemic Infections: subsequent doses, up to 6 gm daily, in divided doses UTI: subsequent doses, up to 4 gm daily in divided doses.”
Sulphamethiazole		100 to 200 mg every four to six hrs.
Sulphamethoxazole	Initial dose, 2 gm;	Subsequent doses, 1 gm two or three times daily.
Tamoxifen Citrate		The equivalent of 20 to 40 mg of Tamoxifen daily as a single dose or in 2 divided doses.
Terbutaline Sulphate		Up to 15 mg daily, in divided doses	By sc inj. 250 to 500 mcg, four times a day.
Testosterone Propionate			By IM inj. 5 to 25 mg, once or twice weekly.
Tetracycline		250 mg every 6 hrs; increased in severe infections to 500 mg every 6 to 8 hrs.
Tetracycline HCl		250 mg every 6 hrs; increased in severe infections to 500 mg every 6 to 8 hrs.	By IM inj. 100 mg every 8 to 12 hrs increased in severe infections to every 4 to 6 hrs; by iv infusion, 500 mg every 12 hrs; maximum 2 gm daily.
Theophylline			By iv infusion, 2.5 to 5.0 mg of anhydrous Theophylline per kg body weight over a period of 20 minutes.

Thiabendazole	Nematode infestation: 1.5 gm twice daily for three days.
Thiacetazone	150 mg daily.
Thiopentone Sodium		By IV inj. initially, 100 to 500 mg repeated if necessary after 20 to 30 seconds; maximum dose, 2 gm.
Thiotepa		300 to 400 mcg per kg of body weight at intervals of 1 to 4 weeks.
Thyroxine Sodium	50 to 300 mcg daily
Tinidazole	“Trichomoniasis: 2 gm as a single dose and after 3 to 5 days rest, if necessary. Giardiasis: 150 mg twice daily for 7 days or as a single dose of 2 gm. Intestinal amoebiasis: 600 mg as a single dose daily for 2 to 6 days.”
Tobramycin		By IM or IV inj. 3 to 5 mg per kg daily, in divided doses.
Tocopheryl Acetate	“Prophylactic: 5 to 10 mg;
Tolbutamide	500 mg to 1.5 gm daily as a single dose with breakfast or in divided doses.
Triamcinolone	2 to 24 mg daily.

Triamcinolone Acetonide		By deep IM inj. 40 to 100 mg.
Triamterene	150 to 250 mg daily, in divided doses.
Tifluoperazine HCl	“Antipsychotic: the equivalent of 2 to 30 mg of Trifluoperazine daily in divided doses. Antiemetic: the equivalent of 2 to 4 mg of Trifluoperazine daily.”	“By IM inj. the equivalent of 1 to 3 mg of Trifluoperazine daily, in divided doses Antiemetic: by im inj. the equivalent of 2 to 3 mg of Trifluoperazine daily in divided doses.”
Trimethoprim	200 mg twice daily.
Triprolidine HCl	10 to 20 mg daily, in divided doses.
Vasopressin Inj.		By sc or IM inj. 2 to 20 Units.
Verapamil HCl	“Antiarrhythmic: 40 to 120 mg thrice daily, Antianginal: 80 to 120 mg Thrice daily; Antihypertensive: 240 to 480 mg daily, in 2 or 3 divided doses;”	By slow IV inj 5 to 10 mg.
Warfarin Sodium	10 to 15 mg.